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Slicer Chest Imaging Platform Reboot

Key Investigators

Project Description

The Chest Imaging Platform (CIP) is an open-source software suite developed by the Applied Chest Imaging Laboratory (ACIL) at Brigham and Women’s Hospital (Harvard Medical School). CIP is designed for quantitative chest CT analysis, helping researchers identify and measure phenotypes for Chronic Obstructive Pulmonary Disease (COPD), Interstitial Lung Disease (ILD), Acute Lung Injury (ALI), and pulmonary vascular pruning, and hopefully by the end of this Lung Cancer.

Objective

This relaunch a modern, deep-learning-centric Chest Imaging Platform within 3D Slicer that simplifies model deployment and optimizes inference, while maintaining core functionalities that are being used for tasks such as lung volume estimation.

Approach and Plan

We address two major historical pain points: Model Dispersion: Previously, integrating new deep learning models required custom scripting or manual installation. We will introduce a unified, user-friendly Model Hub. Further Details pending Pre-processing Discrepancies: Variations in voxel spacing, orientation, and Intensity (Hounsfield Unit) ranges often degrade model performance. We will provide a standardized, automated preprocessing pipeline that ensures input scans are automatically optimized before running inference.

🛠️ System Architecture & Workflow The new Slicer-CIP architecture separates the interactive visualization layer (3D Slicer) from the processing layer, allowing users to pull models from our central repository and execute standardized preprocessing on-the-fly.

Progress and Next Steps

  1. Reviewing current CIP-Slicer integration and getting feedback and development notes from Rubén San José Estépar.

Illustrations

No response

Background and References

  1. Chest Imaging Platform
  2. LobTE